Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29195596 | 1.00 | FUCA1 (0.44) | FUCA1ALDH1A1MAPTGBA1BCHE | |
| SCHEMBL16765361 | 1.00 | FUCA1 (0.44) | FUCA1ALDH1A1MAPTGBA1BCHE | |
| SCHEMBL376328 | 1.00 | FUCA1 (0.44) | FUCA1ALDH1A1MAPTGBA1BCHE | |
| SCHEMBL31309568 | 1.00 | FUCA1 (0.44) | FUCA1ALDH1A1MAPTGBA1BCHE | |
| SCHEMBL19465332 | 1.00 | FUCA1 (0.44) | FUCA1ALDH1A1MAPTGBA1BCHE | |
| SCHEMBL1868761 | 1.00 | FUCA1 (0.44) | FUCA1ALDH1A1MAPTGBA1BCHE | |
| SCHEMBL14428316 | 0.87 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL6802012 | 0.87 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL5387740 | 0.87 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL25595506 | 0.86 | HRH3 (0.46) | FUCA1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300172-B | Bruton tyrosine kinase inhibitors | 比奥根MA公司 | 2024-01-16 | — | — | CN | disclosed |
| WO-2015034729-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AND METHODS OF USE | CALITOR SCIENCES, LLC (US) | 2015-03-12 | — | — | WO | disclosed |
| EP-1643998-A1 | DUAL NK1/NK3 ANTAGONISTS FOR TREATING SCHIZOPHRENIA | F. HOFFMANN-LA ROCHE AG (CH) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005002577-A1 | DUAL NK1/NK3 ANTAGONISTS FOR TREATING SCHIZOPHRENIA | F. HOFFMANN-LA ROCHE AG (CH) | 2005-01-13 | — | — | WO | disclosed |