Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 20/20 | 0.58 |
| ▸ | CCR3 | P51677 | 20/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5787884 | 0.90 | HRH1 (0.57) | HRH1CCR3KCNH2 | |
| SCHEMBL5789430 | 0.85 | HRH1 (0.55) | HRH1CCR3KCNH2 | |
| SCHEMBL5791070 | 0.85 | HRH1 (0.55) | HRH1CCR3KCNH2 | |
| SCHEMBL5338616 | 0.84 | HRH1 (0.69) | HRH1CCR3KCNH2 | |
| SCHEMBL5348492 | 0.84 | HRH1 (0.69) | HRH1CCR3KCNH2 | |
| SCHEMBL5787930 | 0.82 | HRH1 (0.62) | HRH1CCR3KCNH2 | |
| SCHEMBL5788728 | 0.82 | HRH1 (0.61) | HRH1CCR3KCNH2 | |
| SCHEMBL5787507 | 0.82 | CCR3 (0.59) | HRH1CCR3KCNH2 | |
| SCHEMBL5789563 | 0.82 | HRH1 (0.55) | HRH1CCR3KCNH2 | |
| SCHEMBL5791064 | 0.81 | HRH1 (0.59) | HRH1CCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430050-B1 | PIPERIDINE DERIVATIVES AND THEIR USE AS MODULATORS OF CHEMOKINE (ESPECIALLY CCR3) ACTIVITY | ASTRAZENECA AB (SE) | 2006-08-02 | — | — | EP | disclosed |