⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63757 | 1.00 | — | — | |
| SCHEMBL8602076 | 0.82 | — | — | |
| SCHEMBL11344229 | 0.82 | — | — | |
| SCHEMBL9245128 | 0.82 | — | — | |
| SCHEMBL9876840 | 0.82 | — | — | |
| SCHEMBL3125895 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL11190191 | 0.82 | — | — | |
| SCHEMBL4342664 | 0.82 | — | — | |
| SCHEMBL1962877 | 0.71 | — | — | |
| SCHEMBL8434283 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260074-A | Preparation method of Paxlovid intermediate of oral antiviral drug | 爱斯特（成都）生物制药股份有限公司 | 2022-11-01 | — | — | CN | claimed |
| EP-2767541-A1 | LPA receptor agonists and antagonists | Rxbio, Inc. (US) | 2014-08-20 | — | — | EP | claimed |
| CN-115260074-A | Preparation method of Paxlovid intermediate of oral antiviral drug | 爱斯特（成都）生物制药股份有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115141184-A | Ensaitevir preparation method | 杭州国瑞生物科技有限公司 | 2022-10-04 | — | — | CN | disclosed |
| US-8735414-B2 | Indole derivatives and methods for antiviral treatment | PTC THERAPEUTICS, INC. (US) | 2014-05-27 | — | — | US | disclosed |
| US-20120184574-A1 | INDOLE DERIVATIVES AND METHODS FOR ANTIVIRAL TREATMENT | PTC THERAPEUTICS, INC. (US) | 2012-07-19 | — | — | US | disclosed |
| EP-2417122-A1 | INDOLE DERIVATIVES AND METHODS FOR ANTIVIRAL TREATMENT | PTC Therapeutics, Inc. (US) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010117932-A1 | INDOLE DERIVATIVES AND METHODS FOR ANTIVIRAL TREATMENT | SCHERING CORPORATION (US) | 2010-10-14 | — | — | WO | disclosed |
| US-7276484-B2 | Dipeptide inhibitors of β-secretase | ELAN PHARMACEUTICALS, INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050182138-A1 | Dipeptide inhibitors of beta-secretase | ELAN PHARMACEUTICALS, INC. | 2005-08-18 | — | — | US | disclosed |
| US-6900331-B2 | Derivatives of epothilone B and D and synthesis thereof | UNIVERSITY OF NOTRE DAME (US) | 2005-05-31 | — | — | US | disclosed |
| US-6864240-B1 | Dipeptide inhibitors of β-secretase | ELAN PHARMACEUTICALS, INC. (US) | 2005-03-08 | — | — | US | disclosed |
| US-20030176473-A1 | Derivatives of epothilone B and D and synthesis thereof | TAYLOR RICHARD E (US) | 2003-09-18 | — | — | US | disclosed |
| WO-2003074521-A1 | DERIVATIVES OF EPOTHILONE B AND D AND SYNTHESIS THEREOF | UNIVERSITY OF NOTRE DAME (US) | 2003-09-12 | — | — | WO | disclosed |
| WO-2002046200-A1 | MOCVD PRECURSORS BASED ON ORGANOMETALLOID LIGANDS | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2002-06-13 | — | — | WO | disclosed |
| US-6359159-B1 | VAPOR DEPOSITION | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2002-03-19 | — | — | US | disclosed |
| US-6340768-B1 | COMPOUNDS WITH SILICON, GERMANIUM, TIN AND LEAD WITH FLUOROCARBON COMPOUNDS | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2002-01-22 | — | — | US | disclosed |
| US-5284975-A | Method of preparing α-d-phenylalkylbenzyl carbinol | MALLINCKRODT SPECIALTY CHEMICALS COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| US-4374292-A | Process for preparing α-thujene | LION CORPORATION (JP) | 1983-02-15 | — | — | US | disclosed |