Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | GJA1 | P17302 | 1/20 | 0.35 |
| ▸ | GJB2 | P29033 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30089929 | 0.74 | PTPN1 (0.44) | MAPTPTPN1MEN1KMT2ASYNJ2 | |
| SCHEMBL30615017 | 0.74 | PTPN1 (0.44) | MAPTPTPN1MEN1KMT2ASYNJ2 | |
| SCHEMBL20097839 | 0.70 | PTPN1 (0.57) | MAPTPTPN1MEN1KMT2ASYNJ2 | |
| SCHEMBL11288598 | 0.70 | PTPN1 (0.57) | MAPTPTPN1MEN1KMT2ASYNJ2 | |
| SCHEMBL7688096 | 0.70 | PTPN1 (0.57) | MAPTPTPN1MEN1KMT2ASYNJ2 | |
| Trehalose SCHEMBL295383 | 0.69 | MAPT (0.56) | MAPTPTPN1MEN1KMT2AL3MBTL1 | |
| Trehalose SCHEMBL166078 | 0.69 | MAPT (0.56) | MAPTPTPN1MEN1KMT2AL3MBTL1 | |
| Trehalose SCHEMBL6827933 | 0.69 | MAPT (0.56) | MAPTPTPN1MEN1KMT2AL3MBTL1 | |
| Trehalose SCHEMBL15360972 | 0.69 | MAPT (0.56) | MAPTPTPN1MEN1KMT2AL3MBTL1 | |
| Trehalose SCHEMBL7079380 | 0.69 | MAPT (0.56) | MAPTPTPN1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006005142-A2 | MONO- AND POLYCYCLIC COMPOUNDS WITH THERAPEUTIC ACTIVITY, PHARMACEUTICAL COMPOSITIONS INCLUDING THEM AND INTERMEDIATES FOR MAKING THEM | UNIVERSITEIT GENT (BE) | 2006-01-19 | — | — | WO | disclosed |