Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 17/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.55 |
| ▸ | DPP4 | P27487 | 12/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.43 |
| ▸ | FAP | Q12884 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5789163 | 1.00 | DPP8 (0.55) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL5788060 | 0.88 | DPP8 (0.55) | DPP8DPP7DPP4 | |
| SCHEMBL5788128 | 0.82 | DPP8 (0.80) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL5789912 | 0.82 | DPP8 (0.53) | DPP8DPP7DPP4 | |
| SCHEMBL5788734 | 0.81 | DPP8 (0.50) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL5789500 | 0.81 | DPP8 (0.50) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL5790655 | 0.80 | DPP8 (0.54) | DPP8DPP7DPP4 | |
| SCHEMBL5789943 | 0.80 | DPP8 (0.54) | DPP8DPP7DPP4 | |
| SCHEMBL5791172 | 0.79 | DPP8 (0.55) | DPP8DPP7DPP4 | |
| SCHEMBL5788612 | 0.79 | DPP8 (0.50) | DPP8DPP7DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622870-A2 | GLUTAMINYL BASED DP IV-INHIBITORS | Prosidion Ltd. (GB) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004099134-A2 | GLUTAMINYL BASED DP IV-INHIBITORS | PROSIDION LTD. (GB) | 2004-11-18 | — | — | WO | disclosed |
| US-20040229848-A1 | Glutaminyl based DP IV-inhibitors | PROSIDION LIMITED (GB) | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229848-A1 | Glutaminyl based DP IV-inhibitors | DPP4, DPP3, DNPEP | DPP8 7/4885DPP7 5/4885DPP4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.