Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 8/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 17/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791756 | 0.89 | TACR1 (0.41) | NR3C1TACR1CETP | |
| SCHEMBL5793713 | 0.89 | TACR1 (0.47) | NR3C2NR3C1TACR1CETP | |
| SCHEMBL5790053 | 0.87 | TACR1 (0.42) | NR3C2NR3C1TACR1CETP | |
| SCHEMBL5791612 | 0.85 | TACR1 (0.42) | TACR1CETP | |
| SCHEMBL5821974 | 0.84 | TACR1 (0.44) | TACR1CETP | |
| SCHEMBL5793395 | 0.83 | TACR1 (0.49) | TACR1CETP | |
| SCHEMBL5792826 | 0.83 | TACR1 (0.41) | TACR1CETP | |
| SCHEMBL5790666 | 0.81 | TACR1 (0.47) | TACR1CETP | |
| SCHEMBL5793711 | 0.79 | TACR1 (0.47) | TACR1CETP | |
| SCHEMBL5793709 | 0.79 | TACR1 (0.47) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006014942-A1 | ARYLOXYALKYLAMINE NK-1/SSRI INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-02-09 | — | — | WO | claimed |
| WO-2006014942-A1 | ARYLOXYALKYLAMINE NK-1/SSRI INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-02-09 | — | — | WO | disclosed |