Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 14/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14581615 | 1.00 | TRPV1 (0.44) | TRPV1 | |
| SCHEMBL14581619 | 0.88 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL5446553 | 0.88 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL5794283 | 0.86 | TRPV1 (0.56) | TRPV1 | |
| SCHEMBL5446901 | 0.86 | TRPV1 (0.56) | TRPV1 | |
| SCHEMBL14581578 | 0.84 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL5443254 | 0.84 | TRPV1 (0.46) | TRPV1 | |
| SCHEMBL5444489 | 0.84 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL5794013 | 0.84 | TRPV1 (0.46) | TRPV1 | |
| SCHEMBL14581564 | 0.84 | TRPV1 (0.47) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651636-A1 | SUBSTITUTED HETEROCYCLIC DIARYLAMINE ANALOGUES | NEUROGEN CORPORATION (US) | 2006-05-03 | — | — | EP | claimed |
| WO-2005007646-A1 | SUBSTITUTED HETEROCYCLIC DIARYLAMINE ANALOGUES | NEUROGEN CORPORATION (US) | 2005-01-27 | — | — | WO | claimed |