Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NNMT | P40261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11605385 | 0.82 | TDP1 (0.71) | POLBTDP1RAB9ANPC1HPGD | |
| SCHEMBL29859234 | 0.76 | TDP1 (1.00) | POLBTDP1RAB9ANPC1HPGD | |
| SCHEMBL8443874 | 0.76 | POLB (0.73) | POLBTDP1RAB9ANPC1HPGD | |
| SCHEMBL31141991 | 0.76 | POLB (0.73) | POLBTDP1RAB9ANPC1HPGD | |
| SCHEMBL198490 | 0.76 | TDP1 (1.00) | POLBTDP1RAB9ANPC1HPGD | |
| SCHEMBL6409775 | 0.76 | POLB (0.63) | POLBTDP1RAB9ANPC1HPGD | |
| Hydrochloric Acid SCHEMBL10988320 | 0.75 | TDP1 (0.96) | POLBTDP1RAB9ANPC1HPGD | |
| SCHEMBL3864064 | 0.75 | POLB (0.71) | POLBTDP1RAB9ANPC1HPGD | |
| SCHEMBL5010608 | 0.75 | POLB (0.71) | POLBTDP1RAB9ANPC1HPGD | |
| SCHEMBL14946913 | 0.73 | POLB (0.63) | POLBTDP1RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012277-A2 | BIOCATALYTIC PROCESS FOR PREPARING ENANTIOMERICALLY ENRICHED PRAMIPEXOLE | AMR TECHNOLOGY, INC. (US) | 2006-02-02 | — | — | WO | disclosed |