Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 18/20 | 0.65 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.65 |
| ▸ | PDE4A | P27815 | 16/20 | 0.65 |
| ▸ | PDE4C | Q08493 | 15/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797196 | 0.90 | PDE4B (0.52) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL5797194 | 0.89 | PDE4B (0.52) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL5794189 | 0.88 | PDE4D (0.50) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL4126031 | 0.83 | PDE4D (0.61) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL5796349 | 0.82 | PDE4B (0.69) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL2518447 | 0.82 | PDE4D (0.66) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL4544198 | 0.82 | PDE4B (0.71) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| Roflumilast SCHEMBL19158 | 0.79 | PDE4B (1.00) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL6571717 | 0.79 | PDE4D (0.61) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL2887750 | 0.79 | PDE4B (0.92) | PDE4DPDE4BPDE4APDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006040645-A1 | N-(3,5-DICHLOROPYRIDIN-4-YL)-2,4,5-ALKOXY AND 2,3,4-ALKOXY BENZAMIDE DERIVATIVES AS PDE-IV (PHOPHODIESTERASE TYPE-IV) INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES SUCH AS ASTHMA | RANBAXY LABORATORIES LIMITED (IN) | 2006-04-20 | — | — | WO | claimed |
| WO-2006040645-A1 | N-(3,5-DICHLOROPYRIDIN-4-YL)-2,4,5-ALKOXY AND 2,3,4-ALKOXY BENZAMIDE DERIVATIVES AS PDE-IV (PHOPHODIESTERASE TYPE-IV) INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES SUCH AS ASTHMA | RANBAXY LABORATORIES LIMITED (IN) | 2006-04-20 | — | — | WO | disclosed |