Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 12/20 | 0.78 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4976054 | 1.00 | OPRL1 (0.78) | OPRL1MCHR1KCNH2 | |
| SCHEMBL4981676 | 0.98 | OPRL1 (0.78) | OPRL1MCHR1KCNH2 | |
| SCHEMBL4977760 | 0.94 | OPRL1 (0.75) | OPRL1MCHR1KCNH2 | |
| Citric Acid SCHEMBL4975702 | 0.92 | OPRL1 (0.69) | OPRL1MCHR1KCNH2 | |
| Citric Acid SCHEMBL4975902 | 0.90 | OPRL1 (0.69) | OPRL1MCHR1KCNH2 | |
| SCHEMBL4975943 | 0.90 | OPRL1 (0.76) | OPRL1MCHR1 | |
| SCHEMBL4977721 | 0.90 | OPRL1 (0.82) | OPRL1MCHR1KCNH2 | |
| SCHEMBL4977310 | 0.89 | OPRL1 (0.74) | OPRL1MCHR1 | |
| SCHEMBL4977890 | 0.87 | OPRL1 (1.00) | OPRL1MCHR1 | |
| SCHEMBL4976391 | 0.87 | OPRL1 (0.78) | OPRL1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732893-A2 | ALPHA ARYL OR HETEROARYL METHYL BETA PIPERIDINO PROPANAMIDE COMPOUNDS AS ORL1-RECEPTOR ANTAGONIST | Pfizer Japan, Inc. (JP) | 2006-12-20 | — | — | EP | claimed |
| WO-2005092858-A2 | ALPHA ARYL OR HETEROARYL METHYL BETA PIPERIDINO PROPANAMIDE COMPOUNDS AS ORL1-RECEPTOR ANTAGONIST | PFIZER JAPAN INC. (JP) | 2005-10-06 | — | — | WO | claimed |
| EP-1732893-A2 | ALPHA ARYL OR HETEROARYL METHYL BETA PIPERIDINO PROPANAMIDE COMPOUNDS AS ORL1-RECEPTOR ANTAGONIST | Pfizer Japan, Inc. (JP) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092858-A2 | ALPHA ARYL OR HETEROARYL METHYL BETA PIPERIDINO PROPANAMIDE COMPOUNDS AS ORL1-RECEPTOR ANTAGONIST | PFIZER JAPAN INC. (JP) | 2005-10-06 | — | — | WO | disclosed |