Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4287094 | 0.95 | POLB (0.32) | THRATHRBPOLBPKMLMNA | |
| SCHEMBL4296545 | 0.90 | SPHK1 (0.40) | SPHK1THRATHRBPOLBPKM | |
| SCHEMBL4296065 | 0.90 | SPHK1 (0.40) | SPHK1THRATHRBPOLBPKM | |
| SCHEMBL4288416 | 0.89 | DRD4 (0.33) | POLBPKMLMNAMAPTMEN1 | |
| SCHEMBL4288406 | 0.89 | DRD4 (0.33) | POLBPKMLMNAMAPTMEN1 | |
| SCHEMBL4288626 | 0.89 | SPHK1 (0.33) | SPHK1THRATHRBMAPTMEN1 | |
| SCHEMBL4300194 | 0.89 | SPHK1 (0.33) | SPHK1THRATHRBMAPTMEN1 | |
| SCHEMBL4298739 | 0.88 | TSHR (0.33) | MAPTMEN1KMT2AS1PR1 | |
| SCHEMBL5796210 | 0.87 | TSHR (0.33) | MAPTMEN1KMT2AS1PR1 | |
| SCHEMBL4287267 | 0.86 | CNR2 (0.34) | POLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006043149-A2 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIOPROJET (FR) | 2006-04-27 | — | — | WO | claimed |