Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.37 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4287098 | 0.95 | CNR2 (0.35) | — | |
| SCHEMBL4296068 | 0.91 | SPHK1 (0.43) | SPHK1SPHK2EPHX1EPHX2HAO1 | |
| SCHEMBL4288412 | 0.89 | CNR2 (0.36) | SPHK1 | |
| SCHEMBL4288421 | 0.89 | CNR2 (0.36) | SPHK1 | |
| SCHEMBL4288628 | 0.88 | CNR2 (0.37) | SPHK1CCR2EPHX1EPHX2MAPT | |
| SCHEMBL4300197 | 0.88 | CNR2 (0.37) | SPHK1CCR2EPHX1EPHX2MAPT | |
| SCHEMBL4294299 | 0.88 | CNR2 (0.35) | — | |
| SCHEMBL4298741 | 0.87 | CNR2 (0.35) | — | |
| SCHEMBL5796212 | 0.86 | CNR2 (0.35) | — | |
| SCHEMBL4287270 | 0.86 | CNR2 (0.38) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006043149-A2 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIOPROJET (FR) | 2006-04-27 | — | — | WO | claimed |