⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841657 | 0.68 | — | — | |
| SCHEMBL18676691 | 0.67 | — | — | |
| SCHEMBL19069177 | 0.61 | — | — | |
| SCHEMBL28253550 | 0.60 | — | — | |
| SCHEMBL581025 | 0.59 | — | — | |
| SCHEMBL1062527 | 0.59 | — | — | |
| SCHEMBL9918352 | 0.58 | — | — | |
| SCHEMBL25437089 | 0.56 | — | — | |
| SCHEMBL7284433 | 0.56 | — | — | |
| SCHEMBL4694304 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10654810-B2 | Inhibitors of lysine specific demethylase-1 | CELGENE QUANTICEL RESEARCH, INC. (US) | 2020-05-19 | — | — | US | disclosed |
| US-20180325900-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | QUANTIEL PHARMACEUTICALS, INC. | 2018-11-15 | — | — | US | disclosed |
| US-9573930-B2 | Inhibitors of lysine specific demethylase-1 | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-02-21 | — | — | US | disclosed |
| US-20160130247-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | QUANTIEL PHARMACEUTICALS, INC. | 2016-05-12 | — | — | US | disclosed |
| US-20150315187-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | CELGENE QUANTICEL RESEARCH, INC. | 2015-11-05 | — | — | US | disclosed |
| EP-2417112-B1 | SULFONIC AMIDE AND SULFOXIMINE-SUBSTITUTED DIARYL-DIHYDROPYRIMIDINONES AND USAGE THEREOF | BAYER IP GMBH (DE) | 2014-07-09 | — | — | EP | disclosed |
| US-20120094968-A1 | SULFONIC AMIDE AND SULFOXIMINE-SUBSTTTUTED DIARYL-DIHYDROPYRIMIDINONES AND USAGE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-04-19 | — | — | US | disclosed |
| EP-2417112-A1 | SULFONIC AMIDE AND SULFOXIMINE-SUBSTITUTED DIARYL-DIHYDROPYRIMIDINONES AND USAGE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010115548-A1 | SULFONIC AMIDE AND SULFOXIMINE-SUBSTITUTED DIARYL-DIHYDROPYRIMIDINONES AND USAGE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-10-14 | — | — | WO | disclosed |