Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28757934 | 0.90 | MAOB (0.47) | MAPTBACE1MEN1KMT2AMAOB | |
| SCHEMBL5420390 | 0.88 | MEN1 (0.48) | MAPTBACE1MEN1KMT2ANPC1 | |
| SCHEMBL27643530 | 0.87 | MEN1 (0.43) | MAPTBACE1MEN1KMT2ANPC1 | |
| SCHEMBL1231888 | 0.86 | MAPT (0.43) | MAPTBACE1MEN1KMT2ANPC1 | |
| SCHEMBL1231886 | 0.86 | MAPT (0.43) | MAPTBACE1MEN1KMT2ANPC1 | |
| SCHEMBL1486746 | 0.85 | NPC1 (0.46) | MAPTBACE1MEN1KMT2ANPC1 | |
| SCHEMBL6807857 | 0.85 | MAPT (0.41) | MAPTBACE1MEN1KMT2ANPC1 | |
| SCHEMBL311966 | 0.84 | MEN1 (0.43) | MAPTBACE1MEN1KMT2ANPC1 | |
| SCHEMBL3875764 | 0.84 | MAPT (0.44) | MAPTBACE1MEN1KMT2ANPC1 | |
| SCHEMBL1231816 | 0.84 | MAPT (0.42) | MAPTBACE1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006028451-A1 | 1-AMINO 1-H-IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-16 | — | — | WO | disclosed |