Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 17/20 | 0.51 |
| ▸ | FGFR4 | P22455 | 16/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4395804 | 1.00 | FGFR1 (0.51) | FGFR1FGFR4FGFR2FGFR3KIT | |
| SCHEMBL4398490 | 0.89 | FGFR4 (0.45) | FGFR1FGFR4FGFR2FGFR3KIT | |
| SCHEMBL6230890 | 0.89 | FGFR4 (0.45) | FGFR1FGFR4FGFR2FGFR3KIT | |
| SCHEMBL4399127 | 0.87 | FGFR1 (0.50) | FGFR1FGFR4FGFR2FGFR3KIT | |
| SCHEMBL6223699 | 0.85 | FGFR1 (0.51) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL4398987 | 0.85 | FGFR1 (0.51) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL4398196 | 0.84 | FGFR4 (0.52) | FGFR1FGFR4FGFR2FGFR3KIT | |
| SCHEMBL4398327 | 0.83 | FGFR4 (0.54) | FGFR1FGFR4FGFR2FGFR3KIT | |
| SCHEMBL4398700 | 0.83 | FGFR4 (0.57) | FGFR1FGFR4FGFR2FGFR3KIT | |
| SCHEMBL4398255 | 0.82 | FGFR4 (0.52) | FGFR1FGFR4FGFR2FGFR3KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038112-A1 | USE OF KINASE INHIBITORS TO PROMOTE NEOCHONDROGENESIS | WARNER-LAMBERT COMPANY LLC (US) | 2006-04-13 | — | — | WO | disclosed |