Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 13/20 | 0.54 |
| ▸ | DRD2 | P14416 | 9/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | HTR7 | P34969 | 5/20 | 0.44 |
| ▸ | HTR6 | P50406 | 4/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764322 | 0.84 | HTR2A (0.58) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL5766918 | 0.79 | HTR2A (0.52) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL5767235 | 0.79 | HTR2A (0.54) | HTR2ADRD2HTR1AHTR7DRD4 | |
| SCHEMBL6187784 | 0.76 | HTR2A (0.70) | HTR2ADRD2HTR1AHTR7DRD4 | |
| SCHEMBL6187878 | 0.74 | HTR2A (0.70) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL6218382 | 0.74 | HTR2A (0.48) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL6221991 | 0.70 | HTR2A (0.50) | HTR2ADRD2HTR1A | |
| SCHEMBL6186885 | 0.70 | HTR2A (0.57) | HTR2ADRD2HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL6745063 | 0.69 | HTR2A (0.49) | HTR2ADRD2HTR1A | |
| SCHEMBL5767115 | 0.69 | HTR2A (0.57) | HTR2ADRD2HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701954-A1 | N-SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES | Warner-Lambert Company LLC (US) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005066165-A1 | N-SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2005-07-21 | — | — | WO | disclosed |