Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 18/20 | 0.73 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798839 | 0.99 | CASR (0.71) | CASRNR1I2MAPT | |
| SCHEMBL5798841 | 0.99 | CASR (0.71) | CASRNR1I2MAPT | |
| SCHEMBL5799432 | 0.89 | CASR (0.67) | CASRNR1I2MAPT | |
| SCHEMBL5799707 | 0.88 | CASR (0.66) | CASRNR1I2MAPT | |
| SCHEMBL3382473 | 0.88 | CASR (0.76) | CASRNR1I2MAPT | |
| SCHEMBL5797799 | 0.88 | CASR (0.58) | CASRNR1I2 | |
| SCHEMBL5799715 | 0.87 | CASR (0.62) | CASRNR1I2 | |
| SCHEMBL5822471 | 0.86 | CASR (0.73) | CASRNR1I2MAPT | |
| SCHEMBL5823509 | 0.85 | CASR (0.71) | CASRNR1I2MAPT | |
| SCHEMBL5823507 | 0.85 | CASR (0.71) | CASRNR1I2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006066070-A2 | PRODRUG CONSTRUCTS OF PYRIMIDINONE COMPOUNDS AS CALCILYTICS | NPS PHARMACEUTICALS, INC. (US) | 2006-06-22 | — | — | WO | claimed |