Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543263 | 0.86 | — | — | |
| SCHEMBL8214585 | 0.77 | CHRM5 (0.36) | NPC1RAB9AL3MBTL1ADH1BADH1C | |
| SCHEMBL6147682 | 0.76 | NPC1 (0.34) | NPC1RAB9AL3MBTL1ADH1BADH1C | |
| SCHEMBL8214584 | 0.75 | CYP1A2 (0.39) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL16344920 | 0.74 | NPC1 (0.33) | NPC1RAB9AL3MBTL1ADH1BADH1C | |
| SCHEMBL7853296 | 0.74 | NPC1 (0.33) | NPC1RAB9AL3MBTL1ADH1BADH1C | |
| SCHEMBL8143723 | 0.74 | NPC1 (0.33) | NPC1RAB9AL3MBTL1ADH1BADH1C | |
| SCHEMBL28870491 | 0.74 | NPC1 (0.37) | NPC1RAB9AL3MBTL1ADH1BADH1C | |
| SCHEMBL237734 | 0.74 | CYP1A2 (0.37) | NPC1RAB9AL3MBTL1ADH1BADH1C | |
| SCHEMBL17553227 | 0.74 | NPC1 (0.33) | NPC1RAB9AL3MBTL1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554272-B1 | BENZIMIDAZOLES AND BENZOTHIAZOLES AS INHIBITORS OF MAP KINASE | LILLY CO ELI (US) | 2006-10-25 | — | — | EP | claimed |