Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK11 | Q15759 | 9/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 8/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.35 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795644 | 0.95 | MAPK11 (0.52) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL5795840 | 0.93 | MAPK11 (0.48) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL5795633 | 0.90 | MAPK11 (0.49) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL5798471 | 0.89 | MAPK11 (0.52) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL5795927 | 0.88 | MAPK11 (0.53) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL5796468 | 0.86 | MAPK11 (0.52) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL5795836 | 0.85 | MAPK13 (0.48) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL5795756 | 0.79 | MAPK11 (0.61) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL5799438 | 0.79 | MAPK11 (0.61) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL5798634 | 0.75 | MAPK14 (0.52) | MAPK11MAPK14MAPK13MAPK12CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038734-A1 | PYRIDAZINONE DERIVATIVES CYTOKINES INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2006-04-13 | — | — | WO | disclosed |