Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.62 |
| ▸ | ACHE | P22303 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | RAD52 | P43351 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796590 | 1.00 | HRH3 (0.62) | HRH3ACHETSHRRAD52 | |
| SCHEMBL5796592 | 1.00 | HRH3 (0.62) | HRH3ACHETSHRRAD52 | |
| SCHEMBL5793703 | 0.98 | HRH3 (0.60) | HRH3ACHETSHRRAD52 | |
| SCHEMBL5793702 | 0.98 | HRH3 (0.60) | HRH3ACHETSHRRAD52 | |
| SCHEMBL5908120 | 0.98 | HRH3 (0.60) | HRH3ACHETSHRRAD52 | |
| SCHEMBL5795664 | 0.97 | HRH3 (0.61) | HRH3ACHETSHRRAD52 | |
| SCHEMBL5795665 | 0.97 | HRH3 (0.61) | HRH3ACHETSHRRAD52 | |
| SCHEMBL5795661 | 0.97 | HRH3 (0.61) | HRH3ACHETSHRRAD52 | |
| SCHEMBL5795634 | 0.94 | HRH3 (0.59) | HRH3ACHETSHRRAD52 | |
| SCHEMBL5795639 | 0.94 | HRH3 (0.59) | HRH3ACHETSHRRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006024955-A1 | AZABICYCLIC AMINE HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2006-03-09 | — | — | WO | claimed |
| US-20060047114-A1 | Azabicyclic amine histamine-3 receptor antagonists | PFIZER INC | 2006-03-02 | — | — | US | claimed |
| WO-2006024955-A1 | AZABICYCLIC AMINE HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2006-03-09 | — | — | WO | disclosed |
| US-20060047114-A1 | Azabicyclic amine histamine-3 receptor antagonists | PFIZER INC | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047114-A1 | Azabicyclic amine histamine-3 receptor antagonists | HRH3, HRH4, HRH2 | HRH3 1/4885ACHE 227/4885TSHR 535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.