Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2098192 | 0.79 | HTT (0.62) | MEN1KMT2AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL9731379 | 0.78 | CYP3A4 (0.69) | MEN1KMT2AHTTALDH1A1TSHR | |
| SCHEMBL5796044 | 0.76 | GRM4 (0.57) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9298899 | 0.74 | HPGD (0.67) | SMN1; SMN2LMNAALDH1A1MAPTPOLB | |
| SCHEMBL9730148 | 0.74 | GRM4 (0.56) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3970414 | 0.74 | SMN1; SMN2 (0.68) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL10448976 | 0.72 | SMN1; SMN2 (0.66) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL29663501 | 0.72 | SMN1; SMN2 (0.66) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL20679550 | 0.72 | SMN1; SMN2 (0.66) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL27413036 | 0.72 | GRM4 (0.59) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006015279-A1 | HETEROCYCLIC DIAMINE COMPOUNDS AS LIGANDS OF THE MELANIN CONCENTRATING HORMONE RECEPTOR USEFUL FOR THE TREATMENT OF OBESITY, DIABETES, EATING AND SEXUAL DISORDERS | NEUROGEN CORPORATION (US) | 2006-02-09 | — | — | WO | claimed |