Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796656 | 0.92 | HDAC6 (0.47) | HDAC6PKMSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5799746 | 0.91 | HDAC6 (0.41) | HDAC6PKMMAPK1SMN1; SMN2RXFP1 | |
| SCHEMBL5810902 | 0.91 | HDAC6 (0.55) | HDAC6PKMMAPK1SMN1; SMN2RXFP1 | |
| SCHEMBL5799635 | 0.90 | HDAC6 (0.45) | HDAC6KMT2AMEN1CTDSP1TDP1 | |
| SCHEMBL5798867 | 0.90 | HDAC6 (0.45) | HDAC6PKMSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5796521 | 0.89 | PLA2G4B (0.47) | HDAC6PKMKMT2AMEN1CTDSP1 | |
| SCHEMBL5796116 | 0.87 | HDAC6 (0.42) | HDAC6SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL5799534 | 0.87 | POLB (0.42) | HDAC6PKMSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5813256 | 0.86 | HDAC6 (0.44) | HDAC6SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL5798752 | 0.84 | HDAC6 (0.60) | HDAC6PKMSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |