Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510899 | 0.77 | FYN (0.32) | — | |
| SCHEMBL9362202 | 0.70 | HTR2A (0.39) | HTR2AGRM2RARB | |
| SCHEMBL8997231 | 0.70 | CYP2C9 (0.44) | HTR2AGRM2APPCYP3A4CYP2C9 | |
| SCHEMBL9362207 | 0.70 | HTR2A (0.39) | HTR2AGRM2RARB | |
| SCHEMBL8997238 | 0.70 | CYP2C9 (0.44) | HTR2AGRM2APPCYP3A4CYP2C9 | |
| SCHEMBL9362197 | 0.69 | APP (0.39) | APPCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9260405 | 0.68 | CYP2C9 (0.47) | HTR2AGRM2APPCYP3A4CYP2C9 | |
| SCHEMBL9260400 | 0.68 | CYP2C9 (0.47) | HTR2AGRM2APPCYP3A4CYP2C9 | |
| SCHEMBL5892548 | 0.68 | RARB (0.44) | RARB | |
| SCHEMBL10659332 | 0.66 | CYP2A6 (0.37) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006053628-A1 | LIQUID CRYSTAL COMPOUNDS, LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2006-05-26 | — | — | WO | disclosed |