Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5197341 | 1.00 | MAOB (0.38) | MAOBSMN1; SMN2NPC1LMNATP53 | |
| SCHEMBL2248325 | 0.88 | NPC1 (0.39) | MAOBSMN1; SMN2NPC1LMNATP53 | |
| SCHEMBL2246935 | 0.88 | NPC1 (0.39) | MAOBSMN1; SMN2NPC1LMNATP53 | |
| SCHEMBL5800050 | 0.86 | MAOB (0.39) | MAOBSMN1; SMN2NPC1LMNATP53 | |
| SCHEMBL5198442 | 0.82 | MAOB (0.48) | MAOBSMN1; SMN2NPC1LMNATP53 | |
| SCHEMBL12920621 | 0.80 | ALOX5AP (0.51) | ALOX5AP | |
| SCHEMBL1025071 | 0.80 | ALOX5AP (0.51) | ALOX5AP | |
| SCHEMBL977295 | 0.80 | ALOX5AP (0.51) | ALOX5AP | |
| SCHEMBL5795604 | 0.79 | NPC1 (0.54) | MAOBSMN1; SMN2NPC1LMNATP53 | |
| SCHEMBL2246968 | 0.74 | NPC1 (0.41) | MAOBSMN1; SMN2NPC1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006044602-A9 | DIPHENYL SUBSTITUTED ALKANES AS FLAP INHIIBITORS | MERCK & CO INC (US) | 2006-06-08 | — | — | WO | disclosed |