Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | TPH1 | P17752 | 1/20 | 0.30 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459698 | 0.86 | KCNH2 (0.32) | KCNH2TPH1TPH2 | |
| SCHEMBL5822717 | 0.86 | KCNH2 (0.33) | KCNH2TPH1TPH2 | |
| SCHEMBL5458063 | 0.85 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL5473439 | 0.83 | KCNH2 (0.31) | KCNH2 | |
| SCHEMBL5455611 | 0.83 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL5798757 | 0.80 | — | — | |
| SCHEMBL6528178 | 0.77 | EEF2K (0.33) | — | |
| SCHEMBL5469174 | 0.76 | KCNH2 (0.33) | KCNH2TPH1TPH2 | |
| SCHEMBL5454102 | 0.75 | KCNH2 (0.38) | KCNH2TPH1TPH2 | |
| SCHEMBL5459033 | 0.73 | KCNH2 (0.33) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687296-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | Warner-Lambert Company LLC (US) | 2006-08-09 | — | — | EP | claimed |
| WO-2005049605-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | claimed |