Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 11/20 | 0.61 |
| ▸ | MAPK12 | P53778 | 11/20 | 0.61 |
| ▸ | MAPK11 | Q15759 | 11/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.61 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5770478 | 0.98 | MAPK13 (0.61) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL27744938 | 0.90 | MAPK13 (0.61) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5767418 | 0.89 | MAPK13 (0.63) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL27744989 | 0.89 | MAPK14 (0.60) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5770680 | 0.87 | MAPK13 (0.56) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL27724119 | 0.87 | MAPK13 (0.69) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL27724144 | 0.87 | MAPK13 (0.58) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5770547 | 0.86 | MAPK13 (0.62) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5770142 | 0.86 | MAPK13 (0.72) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5772742 | 0.86 | MAPK13 (0.69) | MAPK13MAPK12MAPK11MAPK14SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988301-B1 | IMIDAZOLYL-CYCLIC ACETALS | AVENTIS PHARMA LTD (GB) | 2006-08-09 | — | — | EP | disclosed |