Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 13/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 13/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 8/20 | 0.51 |
| ▸ | FGFR3 | P22607 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4399093 | 1.00 | FGFR4 (0.52) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL4403932 | 0.93 | FGFR4 (0.55) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL4403935 | 0.93 | FGFR4 (0.55) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL4398591 | 0.93 | FGFR4 (0.53) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL4399266 | 0.92 | FGFR4 (0.54) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL6227057 | 0.92 | FGFR4 (0.54) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL4398560 | 0.89 | FGFR4 (0.54) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL5796391 | 0.89 | FGFR4 (0.54) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL5824139 | 0.88 | FGFR4 (0.50) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL4403196 | 0.86 | FGFR4 (0.51) | FGFR4FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038112-A1 | USE OF KINASE INHIBITORS TO PROMOTE NEOCHONDROGENESIS | WARNER-LAMBERT COMPANY LLC (US) | 2006-04-13 | — | — | WO | disclosed |