Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 18/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798725 | 1.00 | CASR (0.58) | CASRNR1I2TAAR1 | |
| SCHEMBL5799676 | 0.93 | CASR (0.58) | CASRNR1I2 | |
| SCHEMBL5799685 | 0.91 | CASR (0.59) | CASRNR1I2TAAR1 | |
| SCHEMBL5799230 | 0.88 | CASR (0.56) | CASRNR1I2TAAR1 | |
| SCHEMBL5795434 | 0.88 | CASR (0.56) | CASRNR1I2 | |
| SCHEMBL5799687 | 0.87 | CASR (0.56) | CASRNR1I2TAAR1 | |
| SCHEMBL5796633 | 0.87 | CASR (0.56) | CASRNR1I2TAAR1 | |
| SCHEMBL5797824 | 0.87 | CASR (0.56) | CASRNR1I2TAAR1 | |
| SCHEMBL5797799 | 0.84 | CASR (0.58) | CASRNR1I2 | |
| SCHEMBL5797665 | 0.83 | CASR (0.79) | CASRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006066070-A2 | PRODRUG CONSTRUCTS OF PYRIMIDINONE COMPOUNDS AS CALCILYTICS | NPS PHARMACEUTICALS, INC. (US) | 2006-06-22 | — | — | WO | disclosed |