Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 6/20 | 0.70 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4242576 | 0.94 | MAPK13 (0.69) | MAPK13MAPK11CYP2C9MAPK14MAPK12 | |
| SCHEMBL5812510 | 0.88 | MAPK11 (0.56) | MAPK13MAPK11CYP2C9MAPK14MAPK12 | |
| SCHEMBL4247658 | 0.85 | MAPK11 (0.67) | MAPK13MAPK11CYP2C9MAPK14MAPK12 | |
| SCHEMBL29594233 | 0.83 | MAPK11 (0.65) | MAPK13MAPK11CYP2C9MAPK14MAPK12 | |
| SCHEMBL29593891 | 0.83 | MAPK13 (0.65) | MAPK13MAPK11CYP2C9MAPK14MAPK12 | |
| SCHEMBL4541468 | 0.83 | MAPK11 (0.65) | MAPK13MAPK11CYP2C9MAPK14MAPK12 | |
| SCHEMBL4236910 | 0.83 | MAPK13 (0.78) | MAPK13MAPK11CYP2C9MAPK14MAPK12 | |
| SCHEMBL4241057 | 0.83 | MAPK13 (0.65) | MAPK13MAPK11CYP2C9MAPK14MAPK12 | |
| SCHEMBL4241312 | 0.83 | MAPK11 (0.68) | MAPK13MAPK11CYP2C9MAPK14MAPK12 | |
| SCHEMBL4712375 | 0.83 | MAPK13 (0.79) | MAPK13MAPK11CYP2C9MAPK14MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038734-A1 | PYRIDAZINONE DERIVATIVES CYTOKINES INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2006-04-13 | — | — | WO | disclosed |