Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 3/20 | 0.56 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5815639 | 0.75 | TYMP (0.48) | TYMPP2RX4IDO1MEN1KMT2A | |
| SCHEMBL31621004 | 0.73 | TYMP (0.60) | TYMPP2RX4IDO1MEN1KMT2A | |
| SCHEMBL27243901 | 0.73 | TYMP (0.45) | TYMPP2RX4IDO1MEN1KMT2A | |
| SCHEMBL2189433 | 0.73 | TYMP (0.53) | TYMPP2RX4IDO1MEN1KMT2A | |
| SCHEMBL2892389 | 0.71 | TYMP (0.43) | TYMPP2RX4IDO1MEN1KMT2A | |
| SCHEMBL2897883 | 0.71 | TYMP (0.50) | TYMPP2RX4IDO1MEN1KMT2A | |
| SCHEMBL3015728 | 0.69 | TYMP (0.54) | TYMPP2RX4IDO1MEN1KMT2A | |
| SCHEMBL9778105 | 0.68 | TYMP (0.54) | TYMPP2RX4IDO1MEN1KMT2A | |
| SCHEMBL16632478 | 0.68 | TYMP (0.43) | TYMPP2RX4IDO1MEN1KMT2A | |
| SCHEMBL11003826 | 0.67 | CYP3A4 (0.57) | TYMPP2RX4IDO1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |