Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1268701 | 0.81 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL2001265 | 0.80 | EPHX2 (0.65) | TRPV1EPHX2NR1H4 | |
| SCHEMBL2001263 | 0.80 | EPHX2 (0.65) | TRPV1EPHX2NR1H4 | |
| SCHEMBL5947730 | 0.78 | TRPV1 (0.83) | TRPV1EPHX2NR1H4 | |
| SCHEMBL12567953 | 0.77 | EPHX2 (0.80) | TRPV1EPHX2NR1H4 | |
| SCHEMBL12567941 | 0.76 | EPHX2 (0.67) | TRPV1EPHX2NR1H4 | |
| SCHEMBL5800708 | 0.76 | TRPV1 (0.75) | TRPV1 | |
| SCHEMBL5818880 | 0.76 | TRPV1 (0.70) | TRPV1EPHX2NR1H4 | |
| SCHEMBL12619647 | 0.75 | EPHX2 (1.00) | TRPV1EPHX2NR1H4 | |
| SCHEMBL22267361 | 0.75 | TRPV1 (0.73) | TRPV1EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006098554-A1 | NOVEL COMPOUNDS, ISOMER THEREOF OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2006-09-21 | — | — | WO | claimed |
| WO-2006098554-A1 | NOVEL COMPOUNDS, ISOMER THEREOF OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2006-09-21 | — | — | WO | disclosed |