Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.35 |
| ▸ | PPARA | Q07869 | 7/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6425785 | 0.93 | PPARG (0.39) | PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL5560242 | 0.89 | PPARG (0.37) | PPARGPPARAPTGS2AKR1C3AKR1C2 | |
| SCHEMBL5800284 | 0.87 | — | — | |
| SCHEMBL6423768 | 0.82 | PPARG (0.40) | PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL5553995 | 0.82 | PPARG (0.41) | PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL5560089 | 0.82 | PPARG (0.41) | PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL5553997 | 0.82 | PPARG (0.41) | PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL6424132 | 0.81 | AKR1C3 (0.41) | PPARGPTGS2AKR1C3AKR1C2 | |
| SCHEMBL5554496 | 0.80 | PPARG (0.40) | PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL6424987 | 0.80 | PPARG (0.39) | PPARGPPARAAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |