Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DUT | P33316 | 4/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4662853 | 0.69 | CRBN (0.52) | CRBNDDB1TYMPPKMDUT | |
| SCHEMBL2719765 | 0.67 | CRBN (0.54) | CRBNDDB1POLBHSD17B10PKM | |
| SCHEMBL10642564 | 0.67 | CRBN (0.48) | CRBNDDB1POLBHSD17B10PKM | |
| SCHEMBL17243686 | 0.66 | GAA (0.54) | CRBNDDB1POLBHSD17B10DUT | |
| SCHEMBL24923587 | 0.65 | CRBN (0.50) | CRBNDDB1POLBHSD17B10PKM | |
| SCHEMBL24211424 | 0.65 | CRBN (0.50) | CRBNDDB1POLBHSD17B10PKM | |
| SCHEMBL2983403 | 0.65 | CRBN (0.50) | CRBNDDB1POLBHSD17B10PKM | |
| SCHEMBL23950038 | 0.65 | CRBN (0.45) | CRBNDDB1POLBHSD17B10PKM | |
| SCHEMBL1344880 | 0.65 | CRBN (0.50) | CRBNDDB1POLBHSD17B10PKM | |
| SCHEMBL3235862 | 0.65 | CRBN (0.50) | CRBNDDB1POLBHSD17B10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |