Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | TOP1 | P11387 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459018 | 0.87 | KCNH2 (0.35) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5466318 | 0.85 | KCNH2 (0.35) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5455471 | 0.83 | KCNH2 (0.39) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5465212 | 0.81 | KCNH2 (0.38) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5462271 | 0.80 | JAK2 (0.36) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5460712 | 0.80 | KCNH2 (0.49) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5457673 | 0.78 | KCNH2 (0.38) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5458074 | 0.78 | KCNH2 (0.38) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5459785 | 0.77 | KCNH2 (0.43) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5458160 | 0.77 | KCNH2 (0.44) | KCNH2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687296-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | Warner-Lambert Company LLC (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005049605-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |