SCHEMBL5801095

SCHEMBL5801095

CCC/C(F)=C(/C)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 4/20 0.43
HDAC1 Q13547 4/20 0.43
HDAC2 Q92769 4/20 0.43
HDAC8 Q9BY41 4/20 0.43
FFAR3 O14843 3/20 0.43
FNTA P49354 2/20 0.43
FNTB P49356 2/20 0.43
THRB P10828 1/20 0.43
PGGT1B P53609 1/20 0.43
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
TSHR P16473 5/20 0.36
ALDH1A1 P00352 3/20 0.35
AKR1B1 P15121 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
PPARG P37231 6/20 0.32
PPARD Q03181 6/20 0.32
PPARA Q07869 6/20 0.32
HDAC11 Q96DB2 5/20 0.32
GPR84 Q9NQS5 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15545947 1.00 HDAC3 (0.43) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL15545946 1.00 HDAC3 (0.43) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL4223550 0.86 FNTA (0.50) FNTAFNTBTHRBPGGT1BCES2
SCHEMBL11045132 0.86 FNTA (0.50) FNTAFNTBTHRBPGGT1BCES2
SCHEMBL9289313 0.84 FNTA (0.59) FNTAFNTBTHRBPGGT1BCES2
SCHEMBL9289310 0.84 FNTA (0.59) FNTAFNTBTHRBPGGT1BCES2
SCHEMBL4331635 0.82 FNTA (0.62) FNTAFNTBTHRBPGGT1BCES2
SCHEMBL10478367 0.82 FNTA (0.62) FNTAFNTBTHRBPGGT1BCES2
SCHEMBL4788436 0.82 FNTA (0.62) FNTAFNTBTHRBPGGT1BCES2
SCHEMBL8372423 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5213938-A Oxidation of toner compositions XEROX CORPORATION (US) 1993-05-25 US claimed
WO-2006066653-A1 COATING AGENT FOR PRODUCING PLIABLE SCRATCH-RESISTANT COATINGS THAT REPEL DIRT, PLIABLE SCRATCH-RESISTANT SHAPED BODIES THAT REPEL DIRT AND METHOD FOR THEIR PRODUCTION RÖHM GMBH (DE) 2006-06-29 WO disclosed
EP-0911153-B1 Image forming method KONISHIROKU PHOTO IND (JP) 2003-12-10 EP disclosed
US-5928832-A Toner adsorption processes XEROX CORPORATION (US) 1999-07-27 US disclosed
US-5213938-A Oxidation of toner compositions XEROX CORPORATION (US) 1993-05-25 US disclosed
EP-0108420-A2 Image-transmitting synthetic resin rod and process for producing the same MITSUBISHI RAYON CO., LTD. (JP) 1984-05-16 EP disclosed