Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5654779 | 0.99 | ANPEP (0.49) | ANPEPFAAHHDAC1HDAC3HDAC2 | |
| Hydrochloric Acid SCHEMBL5654018 | 0.90 | ANPEP (0.51) | ANPEPALDH1A1DPP8DPP7 | |
| Hydrochloric Acid SCHEMBL5654778 | 0.90 | ANPEP (0.55) | ANPEPDPP8DPP7 | |
| Hydrochloric Acid SCHEMBL5653387 | 0.85 | ANPEP (0.48) | ANPEPKDM4EDPP8DPP7 | |
| SCHEMBL5655177 | 0.85 | MAPT (0.44) | FAAHHDAC1HDAC3HDAC2HDAC4 | |
| Hydrochloric Acid SCHEMBL5738774 | 0.85 | ANPEP (0.46) | ANPEPKMT2ADPP8DPP7 | |
| SCHEMBL5801097 | 0.85 | ANPEP (0.52) | ANPEPFAAHHDAC1HDAC3HDAC2 | |
| Hydrochloric Acid SCHEMBL5653036 | 0.85 | ANPEP (0.47) | ANPEPKMT2ADPP8DPP7 | |
| Hydrochloric Acid SCHEMBL5654569 | 0.84 | ANPEP (0.47) | ANPEPHDAC1HDAC3HDAC2HDAC4 | |
| Hydrochloric Acid SCHEMBL5655162 | 0.84 | ANPEP (0.43) | ANPEPCYP3A4ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697337-A2 | ORNITHINE DERIVATIVES AS PROSTAGLANDIN-E2-AGONISTS OR ANTAGONISTS | Astellas Pharma Inc. (JP) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061475-A2 | ORNITHINE DERIVATIVES AS PROSTAGLANDIN E2 AGONISTS OR ANTAGONISTS | ASTELLAS PHARMA INC. (JP) | 2005-07-07 | — | — | WO | disclosed |