Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | DHPS | P49366 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5782626 | 0.86 | F10 (0.50) | F10DHPSHDAC1HDAC3HDAC4 | |
| SCHEMBL5777471 | 0.85 | F10 (0.48) | F10DHPSHDAC1HDAC3HDAC4 | |
| SCHEMBL5780826 | 0.85 | F10 (0.55) | F10DHPSHDAC1HDAC3HDAC4 | |
| SCHEMBL5784722 | 0.85 | F10 (0.49) | F10DHPSHDAC1HDAC3HDAC4 | |
| SCHEMBL5779859 | 0.85 | F10 (0.48) | F10DHPSHDAC1HDAC3HDAC4 | |
| SCHEMBL5783180 | 0.85 | F10 (0.48) | F10DHPSHDAC1HDAC3HDAC4 | |
| SCHEMBL5782283 | 0.84 | F10 (0.56) | F10DHPSHDAC1HDAC3HDAC4 | |
| SCHEMBL5783769 | 0.84 | F10 (0.48) | F10DHPSHDAC1HDAC3HDAC4 | |
| SCHEMBL5784062 | 0.84 | F10 (0.47) | F10DHPSHDAC1HDAC3HDAC4 | |
| SCHEMBL5781280 | 0.83 | F10 (0.46) | F10DHPSHDAC1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408962-B1 | SUBSTITUTED ISOINDOLES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-03-15 | — | — | EP | disclosed |