Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 8/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010997 | 0.91 | HPGD (0.70) | HPGDLMNAHSD17B10MEN1TP53 | |
| SCHEMBL2013386 | 0.90 | HPGD (0.56) | HPGDLMNAHSD17B10MEN1TP53 | |
| SCHEMBL10545845 | 0.88 | HPGD (0.52) | HPGDLMNAHSD17B10MEN1TP53 | |
| SCHEMBL2226744 | 0.82 | PTPN1 (0.52) | HPGDLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL12732188 | 0.82 | HPGD (0.80) | HPGDLMNAHSD17B10MEN1TP53 | |
| SCHEMBL5786028 | 0.81 | MAOB (0.70) | HPGDLMNAPPARDMAOBMAPT | |
| SCHEMBL10547115 | 0.81 | MAOB (0.62) | HPGDLMNAMEN1KMT2AMAOB | |
| SCHEMBL4269174 | 0.80 | GAA (0.53) | HPGDLMNAHSD17B10MEN1TP53 | |
| SCHEMBL2012737 | 0.80 | HPGD (0.59) | HPGDLMNAHSD17B10MEN1TP53 | |
| SCHEMBL7468850 | 0.80 | HPGD (0.50) | HPGDLMNAHSD17B10MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677783-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | Nicholas Piramal India Limited (IN) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005035495-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2005-04-21 | — | — | WO | disclosed |