SCHEMBL5801178

SCHEMBL5801178

CCc1cccc2ncc3ccccc3c12

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.52
GPR3 P46089 1/20 0.52
ELANE P08246 8/20 0.43
HTT P42858 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP2C19 P33261 1/20 0.39
TNKS2 Q9H2K2 1/20 0.38
PDPK1 O15530 1/20 0.38
CYP1A2 P05177 1/20 0.37
KDM1A O60341 1/20 0.36
MAPT P10636 1/20 0.36
LMNA P02545 1/20 0.36
ALDH1A1 P00352 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9935646 0.88 KDM4E (0.53) KDM4EGPR3HTTMEN1KMT2A
SCHEMBL10976790 0.87 KDM4E (0.49) KDM4EGPR3ELANEPDPK1CYP1A2
SCHEMBL9935648 0.85 KDM4E (0.53) KDM4EGPR3HTTKMT2ACYP2C19
SCHEMBL28203657 0.84 KDM4E (0.46) KDM4EGPR3CYP1A2ALDH1A1
SCHEMBL27279082 0.83 KDM4E (0.52) KDM4EGPR3HTTKMT2ACYP2C19
SCHEMBL28355479 0.83 KDM4E (0.52) KDM4EGPR3ELANEHTTMEN1
SCHEMBL27588351 0.83 KDM4E (0.52) KDM4EGPR3HTTKMT2ACYP2C19
SCHEMBL10977274 0.83 TLR8 (0.47) KDM4EGPR3MAPTALDH1A1SMN1; SMN2
Benzene SCHEMBL28537660 0.82 TLR8 (0.46) KDM4EGPR3MAPTLMNAALDH1A1
Iodide SCHEMBL5144116 0.81 TLR7 (0.46) KDM4EGPR3MAPTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114015726-B Delivery, use and therapeutic application of CRISPR-CAS systems and compositions for targeting disorders and diseases with viral components 布罗德研究所有限公司 2025-06-24 CN disclosed
CN-112218939-B Rapid change in sample temperature for assay 上海宜晟生物科技有限公司 2025-06-13 CN disclosed
CN-113425857-B Delivery and use of CRISPR-CAS systems, vectors and compositions for liver targeting and treatment 布罗德研究所有限公司 2025-05-16 CN disclosed
CN-119913127-A Method for processing nucleic acid sample 生物辐射实验室股份有限公司 2025-05-02 CN disclosed
CN-119662792-A Adaptors and methods for optical detection and sequencing 阿尔缇玛基因组学公司 2025-03-21 CN disclosed
CN-119432800-A Method for processing nucleic acid sample 生物辐射实验室股份有限公司 2025-02-14 CN disclosed
CN-110312800-B Method for processing nucleic acid sample 生物辐射实验室股份有限公司 2025-01-10 CN disclosed
CN-114606228-B Compositions and methods for nucleic acid amplification 杭州智灵龙生物科技有限公司 2025-01-07 CN disclosed
CN-114507715-B Compositions and methods for nucleic acid amplification 杭州智灵龙生物科技有限公司 2025-01-07 CN disclosed
CN-111793621-B Novel compositions, methods and kits for enhancing PCR specificity 生命技术公司 2024-12-10 CN disclosed
CN-116583608-A Methods, compositions, kits and systems for signal enhanced detection of neutralizing targets 哈佛大学校长及研究员协会 2023-08-11 CN disclosed
CN-116583599-A Reprogrammable IscB nucleases and uses thereof 博德研究所 2023-08-11 CN disclosed
CN-116569196-A System and method for processing a sample 西吉尼克斯公司 2023-08-08 CN disclosed
CN-116497097-A System and method for performing digital PCR 生命技术公司 2023-07-28 CN disclosed
CN-116419767-A Reagents for labelling biomolecules 阿尔缇玛基因组学公司 2023-07-11 CN disclosed
CN-108368544-B System and method for performing digital PCR 生命技术公司 2023-06-23 CN disclosed
CN-116134153-A System and method for analyzing biological samples 康比纳蒂股份有限公司 2023-05-16 CN disclosed
CN-116096880-A CRISPR related transposase systems and methods of use thereof 博德研究所 2023-05-09 CN disclosed
EP-1692130-A2 PHENANTHRIDINIUM DERIVATIVES AS DNA BINDING AGENTS University Court of The University of Glasgow (GB) 2006-08-23 EP disclosed
WO-2005054241-A2 PHENANTHRIDINIUM DERIVATIVES AS DNA BINDING AGENTS THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) 2005-06-16 WO disclosed