Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Quinaldine Blue. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 11/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.98 |
| ▸ | HTT | P42858 | 7/20 | 0.98 |
| ▸ | BLM | P54132 | 3/20 | 0.98 |
| ▸ | THRB | P10828 | 1/20 | 0.98 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.98 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.77 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.74 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.74 |
| ▸ | NQO2 | P16083 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 6/20 | 0.73 |
| ▸ | RAB9A | P51151 | 6/20 | 0.73 |
| ▸ | MAPT | P10636 | 6/20 | 0.73 |
| ▸ | LMNA | P02545 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.73 |
| ▸ | PKM | P14618 | 4/20 | 0.73 |
| ▸ | ALPG | P10696 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinaldine Blue SCHEMBL29431896 | 1.00 | MEN1 (0.98) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL29571741 | 1.00 | MEN1 (0.98) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL5847479 | 0.99 | MEN1 (1.00) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL2413213 | 0.99 | MEN1 (1.00) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL29837418 | 0.99 | MEN1 (1.00) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL12302233 | 0.99 | MEN1 (1.00) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL6128354 | 0.99 | MEN1 (1.00) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL12284820 | 0.99 | MEN1 (1.00) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL636794 | 0.98 | MEN1 (0.98) | MEN1KMT2AHTTBLMTHRB | |
| Quinaldine Blue SCHEMBL466982 | 0.98 | MEN1 (0.98) | MEN1KMT2AHTTBLMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 13030 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116850307-B | Application of polypeptide TP-6 in preparation of tumor diagnosis and/or treatment reagent | JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE (CN) | 2026-05-26 | — | — | CN | claimed |
| WO-2026102332-A1 | NERVE AND TUMOR HOMING AGENTS AND METHODS OF USE THEREOF | Blaze Bioscience, Inc. (US) | 2026-05-15 | — | — | WO | claimed |
| US-20260108637-A1 | USES OF PSMA-TARGETING AND TSPO-TARGETING COMPOUNDS FOR EVALUATION OF INJURIES IN THE PERIPHERAL NERVOUS SYSTEM | UNIV JOHNS HOPKINS (US) | 2026-04-23 | — | — | US | claimed |
| EP-4719494-A2 | USES OF PSMA-TARGETING AND TSPO-TARGETING COMPOUNDS FOR EVALUATION OF INJURIES IN THE PERIPHERAL NERVOUS SYSTEM | The Johns Hopkins University (US) | 2026-04-08 | — | — | EP | claimed |
| US-12595356-B2 | Composite particle and use thereof in optical filtration | COLOURSMITH LABS INC. (CA) | 2026-04-07 | — | — | US | claimed |
| EP-4716453-A1 | SEMICONDUCTOR WAFER WITH WAFER PROTECTION MATERIAL WITH LUMINESCENT BASED ADDITIVES | INTEL Corporation (US) | 2026-03-25 | — | — | EP | claimed |
| US-20260082987-A1 | WAFER PROTECTION MATERIAL WITH LUMINESCENT BASED ADDITIVES | INTEL CORP (US) | 2026-03-19 | — | — | US | claimed |
| EP-4705295-A2 | MULTIFUNCTIONAL COMPOUND CORE FOR ACTIVE AGENTS AND USES THEREOF | The University of North Carolina at Chapel Hill (US) | 2026-03-11 | — | — | EP | claimed |
| US-20260048152-A1 | GEMCITABINE INORGANIC-ORGANIC HYBRID NANOPARTICLES | KARLSRUHER INSTITUT FUER TECH KOERPERSCHAFT DES OEFFENTLICHEN RECHTS (DE) | 2026-02-19 | — | — | US | claimed |
| EP-4695308-A1 | ENGINEERED ANTIBODIES AND USES THEREOF | Invitrogen BioServices India Private Limited (IN) | 2026-02-18 | — | — | EP | claimed |
| US-4345470-A | All plastic disposable thermometer | AKZONA INCORPORATED (US) | 1982-08-24 | — | — | US | claimed |
| US-4343891-A | CONVERTING TO COMPOUND HAVING FEWER THAN FOUR CARBON-TO-BORON BONDS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-08-10 | — | — | US | claimed |
| US-4339207-A | Temperature indicating compositions of matter | AKZONA INCORPORATED (US) | 1982-07-13 | — | — | US | claimed |
| US-4307182-A | RADIATION SENSITIVE ELEMENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1981-12-22 | — | — | US | claimed |
| EP-0040977-A1 | Imaging systems with tetra(aliphatic)borate salts | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1981-12-02 | — | — | EP | claimed |
| US-4299727-A | Disposable reversible thermometer | AKZONA INCORPORATED (US) | 1981-11-10 | — | — | US | claimed |
| US-4232552-A | THERMOCHROMISM, DISPOSABLE THERMOMETERS | AKZONA INCORPORATED (US) | 1980-11-11 | — | — | US | claimed |
| US-4015989-A | Color light-sensitive material with spontaneously developable silver halide emulsion containing desensitizing dye | FUJI PHOTO FILM CO., LTD. (JA) | 1977-04-05 | — | — | US | claimed |
| US-3977882-A | CARBOCYANINE DYES | FUJI PHOTO FILM CO., LTD. (JA) | 1976-08-31 | — | — | US | claimed |
| US-3976640-A | CYANINE | POLAROID CORPORATION (US) | 1976-08-24 | — | — | US | claimed |