Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 1.00 |
| ▸ | MEN1 | O00255 | 9/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 0.78 |
| ▸ | GAA | P10253 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 1/20 | 0.78 |
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | PKM | P14618 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.65 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.65 |
| ▸ | PPARG | P37231 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5801289 | 1.00 | KMT2A (1.00) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL29946098 | 0.88 | MEN1 (1.00) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL15043023 | 0.85 | MEN1 (0.74) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL28490585 | 0.83 | MEN1 (0.77) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL28490584 | 0.83 | MEN1 (0.77) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL5150390 | 0.82 | MEN1 (0.81) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL5150395 | 0.82 | MEN1 (0.81) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL13282738 | 0.81 | MEN1 (0.68) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL25208499 | 0.81 | MEN1 (0.78) | KMT2AMEN1MAPTKDM4EPKM | |
| SCHEMBL25208498 | 0.81 | MEN1 (0.78) | KMT2AMEN1MAPTKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006081658-A1 | IN SILICO SCREENING FOR SHBG BINDING LIGANDS VIA PHARMACOPHORE MODELS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2006-08-10 | — | — | WO | disclosed |