Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.61 |
| ▸ | HTR1A | P08908 | 10/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.61 |
| ▸ | HTR2C | P28335 | 6/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23228614 | 0.92 | SLC6A2 (0.66) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL11127696 | 0.89 | PTGDR2 (0.60) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL5780734 | 0.86 | SLC6A4 (0.54) | SLC6A2SLC6A4SLC6A3HTR2CIKBKB | |
| SCHEMBL19240459 | 0.86 | SLC6A2 (0.51) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL23228660 | 0.86 | SLC6A2 (0.58) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL19205459 | 0.85 | SLC6A2 (0.50) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL19205314 | 0.85 | SLC6A2 (0.50) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL19205318 | 0.84 | SLC6A2 (0.52) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL23228750 | 0.84 | SLC6A2 (0.59) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C | |
| SCHEMBL19205356 | 0.84 | SLC6A2 (0.52) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254904-B1 | NOVEL PIPERIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME | EISAI CO LTD (JP) | 2006-05-24 | — | — | EP | disclosed |