Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5470823 | 0.91 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL5462537 | 0.90 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL5466783 | 0.89 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL5452039 | 0.88 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL5799174 | 0.86 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL5798813 | 0.83 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL5801958 | 0.81 | JAK2 (0.35) | KCNH2 | |
| SCHEMBL14432073 | 0.80 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL5459714 | 0.80 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL5800341 | 0.80 | KCNH2 (0.39) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687296-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | Warner-Lambert Company LLC (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005049605-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |