Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459809 | 0.94 | KCNH2 (0.38) | KCNH2SCN5A | |
| SCHEMBL5457750 | 0.93 | KCNH2 (0.37) | KCNH2SCN5AJAK2JAK1TYK2 | |
| SCHEMBL5801490 | 0.87 | KCNH2 (0.32) | KCNH2 | |
| SCHEMBL5466789 | 0.85 | KCNH2 (0.38) | KCNH2SCN5A | |
| SCHEMBL5466372 | 0.84 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL5453097 | 0.84 | KCNH2 (0.38) | KCNH2SCN5AJAK2JAK1TYK2 | |
| SCHEMBL5469009 | 0.84 | KCNH2 (0.34) | KCNH2JAK2JAK1TYK2JAK3 | |
| SCHEMBL5801132 | 0.81 | KCNH2 (0.35) | KCNH2SCN5A | |
| SCHEMBL5798838 | 0.81 | KCNH2 (0.38) | KCNH2SCN5AJAK2JAK1TYK2 | |
| SCHEMBL5800341 | 0.80 | KCNH2 (0.39) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687296-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | Warner-Lambert Company LLC (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005049605-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |