Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4898256 | 0.91 | HDAC1 (0.66) | HDAC1KCNH2HDAC2 | |
| SCHEMBL5797191 | 0.88 | HDAC1 (0.64) | HDAC1KCNH2 | |
| SCHEMBL4892864 | 0.86 | HDAC1 (0.65) | HDAC1KCNH2HDAC2 | |
| SCHEMBL4897259 | 0.86 | HDAC1 (0.69) | HDAC1KCNH2HDAC2 | |
| SCHEMBL4899357 | 0.85 | HDAC1 (0.70) | HDAC1KCNH2HDAC2 | |
| SCHEMBL5315186 | 0.85 | HDAC1 (0.63) | HDAC1HDAC2 | |
| SCHEMBL4895844 | 0.85 | HDAC1 (0.63) | HDAC1KCNH2HDAC2 | |
| SCHEMBL4897024 | 0.85 | HDAC1 (0.63) | HDAC1KCNH2HDAC2 | |
| SCHEMBL4897918 | 0.84 | HDAC1 (0.60) | HDAC1KCNH2HDAC2 | |
| SCHEMBL4887537 | 0.84 | HDAC1 (0.67) | HDAC1KCNH2HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006077387-A2 | NOVEL BENZAMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2006-07-27 | — | — | WO | claimed |