Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.49 |
| ▸ | PPARG | P37231 | 16/20 | 0.49 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5814626 | 1.00 | PPARA (0.49) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL5802240 | 0.94 | PPARA (0.49) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL5815429 | 0.94 | PPARA (0.49) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL5809648 | 0.93 | KDM4E (0.48) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL5823882 | 0.93 | PPARA (0.50) | PPARAPPARGPPARD | |
| SCHEMBL5798061 | 0.93 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL5798063 | 0.93 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL5823886 | 0.93 | PPARA (0.50) | PPARAPPARGPPARD | |
| SCHEMBL5824242 | 0.91 | PPARG (0.47) | PPARAPPARGPPARD | |
| SCHEMBL5824239 | 0.91 | PPARG (0.47) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | claimed |
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |