Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 7/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5815019 | 1.00 | HAVCR2 (0.40) | HAVCR2PPARGPPARAGSTP1NPSR1 | |
| SCHEMBL5815283 | 0.97 | PPARG (0.41) | HAVCR2PPARGPPARA | |
| SCHEMBL5815282 | 0.97 | PPARG (0.41) | HAVCR2PPARGPPARA | |
| SCHEMBL5809974 | 0.93 | NPSR1 (0.43) | HAVCR2PPARGPPARANPSR1SMPD1 | |
| SCHEMBL5809977 | 0.93 | NPSR1 (0.43) | HAVCR2PPARGPPARANPSR1SMPD1 | |
| SCHEMBL5812967 | 0.91 | PPARG (0.45) | PPARGPPARAHTT | |
| SCHEMBL5813984 | 0.91 | PPARG (0.45) | PPARGPPARAHTT | |
| SCHEMBL5812488 | 0.87 | PPARG (0.40) | PPARGPPARATP53HTT | |
| SCHEMBL5799155 | 0.87 | PPARG (0.41) | PPARGPPARAHTTPOLBKMT2A | |
| SCHEMBL5802170 | 0.87 | PPARG (0.42) | HAVCR2PPARGPPARATP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |