SCHEMBL5801970

SCHEMBL5801970

CC(C)(C)c1ccc(/C=C/C(=O)NCc2ccc(NS(C)(=O)=O)c(OC(F)(F)F)c2)cc1

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5801971 1.00 TRPV1 (0.49) TRPV1
SCHEMBL5801197 0.95 TRPV1 (0.49) TRPV1
SCHEMBL5801195 0.95 TRPV1 (0.49) TRPV1
SCHEMBL5800948 0.90 TRPV1 (0.53) TRPV1
SCHEMBL5800951 0.90 TRPV1 (0.53) TRPV1
SCHEMBL1999905 0.85 TRPV1 (0.67) TRPV1
SCHEMBL1999904 0.85 TRPV1 (0.67) TRPV1
SCHEMBL2004108 0.84 TRPV1 (0.52) TRPV1
SCHEMBL2004107 0.84 TRPV1 (0.52) TRPV1
SCHEMBL2005223 0.84 TRPV1 (0.51) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006098554-A1 NOVEL COMPOUNDS, ISOMER THEREOF OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AMOREPACIFIC CORPORATION (KR) 2006-09-21 WO disclosed