Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4275449 | 0.82 | NOTUM (0.60) | NOTUMRAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL5306222 | 0.81 | NOTUM (0.53) | NOTUMRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18490185 | 0.81 | NOTUM (0.46) | NOTUMRAB9ANPC1ALDH1A1CYP11B1 | |
| SCHEMBL5309293 | 0.79 | NOTUM (0.45) | NOTUMRAB9ANPC1CYP2C9TSPO | |
| SCHEMBL16111316 | 0.78 | NOTUM (0.60) | NOTUMRAB9ANPC1ALDH1A1CYP2C9 | |
| SCHEMBL103310 | 0.78 | NOTUM (0.70) | NOTUMRAB9ANPC1CYP2C9TSPO | |
| SCHEMBL4683349 | 0.75 | NOTUM (0.66) | NOTUMRAB9ANPC1ALDH1A1CYP2C9 | |
| SCHEMBL2891062 | 0.75 | NOTUM (0.51) | NOTUMRAB9ANPC1CYP2C9TSPO | |
| SCHEMBL20845555 | 0.74 | NOTUM (0.67) | NOTUMRAB9ANPC1CYP2C9TSPO | |
| SCHEMBL1751803 | 0.73 | NOTUM (0.58) | NOTUMRAB9ANPC1ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006064484-A1 | AZABICYCLONONENE DERIVATIVES AS RENIN INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-06-22 | — | — | WO | disclosed |