Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.87 |
| ▸ | FAP | Q12884 | 1/20 | 0.87 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.87 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.87 |
| ▸ | PREP | P48147 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5803813 | 1.00 | DPP4 (0.87) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL5803394 | 1.00 | DPP4 (0.87) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL5789098 | 0.95 | DPP4 (0.83) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL5805315 | 0.93 | DPP4 (0.77) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL26661289 | 0.93 | DPP4 (0.77) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL26661345 | 0.93 | DPP4 (0.77) | DPP4FAPDPP8DPP9PREP | |
| Vildagliptin SCHEMBL16823370 | 0.93 | DPP4 (1.00) | DPP4FAPDPP8DPP9PREP | |
| Vildagliptin SCHEMBL16579 | 0.93 | DPP4 (1.00) | DPP4FAPDPP8DPP9PREP | |
| Vildagliptin SCHEMBL10031674 | 0.93 | DPP4 (1.00) | DPP4FAPDPP8DPP9PREP | |
| Vildagliptin SCHEMBL671629 | 0.93 | DPP4 (1.00) | DPP4FAPDPP8DPP9PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012441-A1 | PEPTIDASE INHIBITORS | ROYALTY SUSAN MARIE (US) | 2006-02-02 | — | — | WO | disclosed |